Antihistamines, available over the counter and by prescription, block that message. Fineman says. But you may need to allow up to two weeks to see if they help overall. Most people get at least some relief with antihistamines. However, Dr. Lamb says that some individuals may need a combination of antihistamines to control their hives, such as a sedating antihistamine at bedtime and a non-drowsy formula during the day.
Histamines not only cause allergic reactions that can lead to hives, but also stimulate cells in the lining of your stomach that produce hydrochloric acid. Available H2 drugs are nizatidine , famotidine , cimetidine , and ranitidine.
They're only effective for hives when used in combination with first-line antihistamines. These drugs can be taken orally or by injection.
Corticosteroids reduce inflammation. Like antihistamines, they should work rather quickly, Fineman says. Merck Manual Consumer Version. Curcumin: An age-old anti-inflammatory and anti-neoplastic agent. J Tradit Complement Med. Anti-inflammatory activities of colloidal oatmeal Avena sativa contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin. J Drugs Dermatol.
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I Accept Show Purposes. Table of Contents View All. Table of Contents. Home Remedies. Over-the-Counter Remedies. Complementary Medicines CAM. Next in Hives Guide. See Photo. OTC antihistamines may not be strong enough to treat all forms of urticaria. Hives Healthcare Provider Discussion Guide Get our printable guide for your next healthcare provider's appointment to help you ask the right questions.
Download PDF. Email the Guide Send to yourself or a loved one. Sign Up. Frequently Asked Questions What do hives look like? What causes hives? Hives are the result of an abnormal immune response that can be caused by a wide variety of factors , including: Food allergies Medication drug allergies Environmental allergies i. How can I treat hives at home?
Generally, the most effective, first-line treatment for hives is an over-the-counter OTC non-drowsy antihistamine , such as: Allegra fexofenadine Claritin loratadine Xyzal levocetirizine dihydrochloride Zyrtec cetirizine Antihistamine drugs help quell the histamine response that causes hives to form. How can I relieve symptoms of hives? How long do hives typically last?
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Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Bernstein, J.
The very limited evidence provided by this review was based on a few old studies of a relatively small size, which we categorised as having high to unclear risk of bias.
Thus, at present, the review does not allow confident decision-making about the use of H2-receptor antagonists for urticaria. Although some of these studies have reported a measure of relief of symptoms of urticaria and rather minimal clinical improvement in some of the participants, the evidence was weak and unreliable. We have emphasised the lack of precision and limitations in the reported data where appropriate in this review. Urticaria is a common skin disease characterised by itching weals or hives, which can occur almost anywhere on the body.
There are a number of different subtypes and a range of available treatment options. There is lack of agreement on the efficacy of H2-receptor antagonists used in the treatment of urticaria. We also searched online trials registries for ongoing trials. Randomised controlled trials of H2-receptor antagonists in people with a clinical diagnosis of urticaria of any duration or of any subtype.
Studies including H1-antihistamines for chronic urticaria are the topic of a separate Cochrane review; thus, they were not included in this review.
The most prevalent theory is that CIU is an autoimmune-like condition. In people with CIU, we commonly see autoantibodies directed at cells that release histamine mast cells and basophils.
Additionally, these individuals often have other autoimmune disorders such as thyroid disease. Another theory is that there are specific mediators in the serum or plasma of people with CIU. These mediators activate mast cells or basophils, either directly or indirectly. This leads to excess histamine release. Dietary modifications are also not supported by most consensus guidelines. Adherence to diets, such as a low-histamine diet, is also extremely hard to follow.
There are several known triggers that can aggravate your hives. Heat, alcohol, pressure, friction, and emotional stress are well-reported to worsen symptoms.
Additionally, you should consider avoiding aspirin and other nonsteroidal anti-inflammatory drugs NSAIDs. They can aggravate CIU in many cases. You may continue to take low-dose, baby aspirin when used to prevent blood clots. These products include loratadine, cetirizine, levocetirizine, and fexofenadine.
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